Cyclobenzaprine: MedlinePlus Drug Information

Cyclobenzaprine: MedlinePlus Drug Information

Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval. For patients experiencing muscle spasms or severe pain, certain types of medications can help in relieving discomfort and managing symptoms.

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Oral dosages of Chlorzoxazone typically start at 500 mg three or four times per day. However, for some patients, a starting dose of 250 mg may be sufficient for managing muscle spasms. If there is no response after a few weeks, the dosage can be increased to a maximum daily dose of 750 mg three or four times per day. Similarly, Flexeril (cyclobenzaprine) is usually begun at an oral dose of 5 mg three times per day and if needed, it can gradually be increased to 10 mg three times a day depending on patient tolerance and effectiveness. The maximum dosage that should not be exceeded in any case is mg/day.

FAQs About Cyclobenzaprine

While all the medicines are effective, one specific muscle relaxant might work better than others for you. Using drinks containing alcohol can increase your risk of dizziness, drowsiness, and decreased alertness from cyclobenzaprine. Call your doctor or local poison control center if you think you’ve taken too much of this drug.

All patients suspected of an overdose with FLEXERIL should receive gastrointestinal decontamination. This should include large volume gastric lavage followed by activated charcoal. If consciousness is impaired, the airway should be secured prior to lavage and emesis is contraindicated. Less frequent dosing should be considered for hepatically impaired or elderly patients (see PRECAUTIONS, Impaired Hepatic Function, and Use in the Elderly). Our Flexeril (cyclobenzaprine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

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Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. If you notice other effects not listed above, contact your doctor or pharmacist. You are encouraged to report negative side effects of prescription drugs to the FDA. Other potential effects of overdosage include any of the symptoms listed under ADVERSE REACTIONS. For most patients, the recommended dose of Flexeril is 5 mg three times a day.

Avoid or limit the use of alcohol or other sedating medicines while being treated with cyclobenzaprine. Also avoid driving, operating machinery, or other hazardous activities until you know how cyclobenzaprine affects you. Other drugs may interact with cyclobenzaprine, including prescription and over-the-counter medicines, vitamins, and herbal products. Flexeril is a central nervous system (CNS) depressant that is prescribed for the short-term treatment of pain and limitation of motion caused by muscle spasms.

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They act on different aspects of the nervous system but are often prescribed for similar conditions such as musculoskeletal pain or spasms. Skeletal muscle relaxants are prescription medications commonly used to treat muscle pain and muscle spasms. If you have back pain or have suffered a strain or sprain, your healthcare provider may offer you a skeletal muscle relaxant such as methocarbamol (Robaxin) or cyclobenzaprine (Fexmid, Amrix). Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions.

  • Studies show that increased exposure to natural light can also improve sleep.
  • Avoid driving or hazardous activity until you know how this medicine will affect you.
  • Drowsiness, dizziness, dry mouth, constipation, or tiredness may occur.
  • Because cyclobenzaprine is closely related to the tricyclic antidepressants, some of which are known to be excreted in human milk, caution should be exercised when FLEXERIL is administered to a nursing woman.

Flexeril, the brand name for cyclobenzaprine, is a muscle relaxant that works by blocking nerve impulses (or pain sensations) sent to your brain. It was first approved by the FDA in 1977 and is often used alongside physical therapy and rest to treat skeletal muscle conditions such as pain or injury. Unlike Chlorzoxazone, Flexeril does not directly act on the muscles; instead it primarily acts within the central nervous system at brain stem level. This can result in fewer side effects related to direct muscular interaction such as weakness.

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Cyclobenzaprine is considered a skeletal muscle relaxant because of the way it affects the body’s nervous system. Once the drug enters your body, it triggers your brain and nervous system to relax different muscles in the body, simultaneously relieving the pain and discomfort you feel. Muscle relaxers such as these act like a depressant for your body’s central nervous system. This causes a sedative effect and prevents your nerves from sending pain signals to your brain. Cyclobenzaprine is used together with rest and physical therapy to relieve muscle spasms caused by painful conditions such as an injury.

However, they can have some distinctions that you and your doctor should consider when looking for the right medication for your needs. Learn more about how tizanidine and cyclobenzaprine compare. Both Chlorzoxazone and Flexeril (cyclobenzaprine) have a long-standing history of use in the treatment of muscle spasms, backed by extensive clinical studies indicating their efficacy over placebo treatments. They work through different mechanisms, with Chlorzoxazone acting centrally at the spinal cord and subcortical levels while Flexeril targets the brain stem to achieve muscle relaxation. Cyclobenzaprine, under brand names such as Flexeril, was prescribed to approximately 16 million people in USA during that same year. Cyclobenzaprine accounts for nearly half of all muscle relaxant prescriptions in the US.

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